Brognard, J.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Protein kinase signaling networks in cancer

John Brognard, Tony Hunter

Journal:

Current Opinion in Genetics & Development

Year:

2011

Language:

english

File:

PDF, 348 KB

english, 2011

2

Orange is the new black: Kinases are the new master regulators of tumor suppression

An, Elvira, Brognard, John

Journal:

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

3

Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants

Brognard, J, Dennis, P A

Journal:

Cell Death & Differentiation

Year:

2002

Language:

english

File:

PDF, 401 KB

english, 2002

4

The mRNA Surveillance Protein hSMG-1 Functions in Genotoxic Stress Response Pathways in Mammalian Cells

Kathryn M. Brumbaugh, Diane M. Otterness, Christoph Geisen, Vasco Oliveira, John Brognard, Xiaojie Li, Fabrice Lejeune, Randal S. Tibbetts, Lynne E. Maquat, Robert T. Abraham

Journal:

Year:

2004

Language:

english

File:

PDF, 550 KB

english, 2004

5

PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms

John Brognard, Emma Sierecki, Tianyan Gao, Alexandra C. Newton

Journal:

Year:

2007

Language:

english

File:

PDF, 1.43 MB

english, 2007

6

The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress

You-Wei Zhang, John Brognard, Chris Coughlin, Zhongsheng You, Marisa Dolled-Filhart, Aaron Aslanian, Gerard Manning, Robert T. Abraham, Tony Hunter

Journal:

Year:

2009

Language:

english

File:

PDF, 1.10 MB

english, 2009

7

PHLiPPing the switch on Akt and protein kinase C signaling

John Brognard, Alexandra C. Newton

Journal:

Trends in Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 709 KB

english, 2008

8

P-326 Tobacco carcinogen-induced cellular transformation increases Akt activation in vitro and in vivo

West, Kip A., Linnoila, Ilona R., Brognard, John, Belinsky, Steven, Harris, Curtis C., Dennis, Philip A.

Journal:

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

9

PReS-FINAL-2173: Protein kinase C delta deficiency is a new cause of monogenic SLE

Belot, A, Kasher, PK, Trotter, EW, Foray, AP, Debaud, AL, Meffre, E, Brognard, J, Bonnefoy, N, Crow, Y

Journal:

Pediatric Rheumatology

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

10

NOTES

R. Brognard Okie and John Welsh Dulles

Journal:

Journal of the Department of History (The Presbyterian Historical Society) of the Presbyterian Church in the U.S.A.

Year:

1930

Language:

english

File:

PDF, 917 KB

english, 1930

11

Novel PI Analogues Selectively Block Activation of the Pro-survival Serine/Threonine Kinase Akt

Kozikowski, Alan P., Sun, Haiying, Brognard, John, Dennis, Phillip A.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

12

Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output

Reyes, G., Niederst, M., Cohen-Katsenelson, K., Stender, J. D., Kunkel, M. T., Chen, M., Brognard, J., Sierecki, E., Gao, T., Nowak, D. G., Trotman, L. C., Glass, C. K., Newton, A. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

13

504 Frequent loss-of-function mutations in MLK4 suppresses signaling in the JNK-cJUN-p21/p15 pathway to promote growth of colon cancer cells

Marusiak, A., Stephenson, N., Baik, H., Trotter, E., Li, Y., Testoni, E., Blyth, K., Mason, S., Puto, L., Miller, C., Hunter, T., Sansom, O., Brognard, J.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

14

512 Somatically mutated ABL1 represents an actionable and essential lung cancer survival gene

Testoni, E., Stephenson, N.L., Marusiak, A.A., Trotter, E.W., Hudson, A., Brognard, J.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

15

Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery

Hudson, A. M., Yates, T., Li, Y., Trotter, E. W., Fawdar, S., Chapman, P., Lorigan, P., Biankin, A., Miller, C. J., Brognard, J.

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 501 KB

english, 2014

16

Common Polymorphism in the Phosphatase PHLPP2 Results in Reduced Regulation of Akt and Protein Kinase C

Brognard, J., Niederst, M., Reyes, G., Warfel, N., Newton, A. C.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

17

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer

Fawdar, S., Trotter, E. W., Li, Y., Stephenson, N. L., Hanke, F., Marusiak, A. A., Edwards, Z. C., Ientile, S., Waszkowycz, B., Miller, C. J., Brognard, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 871 KB

english, 2013

18

Reply

Belot, Alexandre, Brognard, John, Crow, Yanick J., Bonnefoy, Nathalie

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 69 KB

english, 2014

19

The Phosphatase PHLPP Controls the Cellular Levels of Protein Kinase C

Gao, T., Brognard, J., Newton, A. C.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1003 KB

english, 2008

20

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

West, Kip A., Brognard, John, Clark, Amy S., Linnoila, Ilona R., Yang, Xiaowei, Swain, Sandra M., Harris, Curtis, Belinsky, Steven, Dennis, Phillip A.

Journal:

Journal of Clinical Investigation

Year:

2003

Language:

english

File:

PDF, 1.58 MB

english, 2003

21

Transcriptional Repressor DAXX Promotes Prostate Cancer Tumorigenicity via Suppression of Autophagy

Puto, Lorena A., Brognard, John, Hunter, Tony

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 6.23 MB

english, 2015

22

Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges

Hudson, Andrew M, Wirth, Christopher, Stephenson, Natalie L, Fawdar, Shameem, Brognard, John, Miller, Crispin J

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

23

Cancer-Associated Loss-of-Function Mutations Implicate DAPK3 as a Tumor-Suppressing Kinase

Brognard, J., Zhang, Y.-W., Puto, L. A., Hunter, T.

Journal:

Cancer Research

Year:

2011

Language:

english

File:

PDF, 2.69 MB

english, 2011

24

La Préhistoire aux Armées: Hache polie en silex

Lucien BROGNARD

Journal:

Bulletin de la Société préhistorique de France

Year:

1919

File:

PDF, 167 KB

1919

25

Lillebonne Préhistorique

Lucien BROGNARD

Journal:

Bulletin de la Société préhistorique de France

Year:

1919

File:

PDF, 522 KB

1919

26

Tobacco Carcinogen-Induced Cellular Transformation Increases Akt Activation In Vitro and In Vivo

West, Kip A., Linnoila, Ilona R., Brognard, John, Belinsky, Steven, Harris, Curtis, Dennis, Phillip A.

Journal:

Year:

2004

Language:

english

File:

PDF, 84 KB

english, 2004

27

The TARGET trial: Molecular profiling of circulating tumour DNA to stratify patients to early phase clinical trials

Rothwell, Dominic, Ayub, Mahmood, Gulati, Sakshi, Brognard, John, Wallace, Andrew, Miller, Crispin, Dean, Emma J., Cook, Natalie, Thistlethwaite, Fiona, Leong, Hui Sun, Eaton, Helen, Howard, Emma, Hud

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2016

Language:

english

File:

PDF, 67 KB

english, 2016

28

Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor

Newton, Alexandra C., Brognard, John

Journal:

Trends in Pharmacological Sciences

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

29

3: Germline sequencing of DIPNECH patients reveals a heterogeneous disease with novel SNVs in genes that are somatically mutated in other neuroendocrine malignancies

Hudson, A.M., Leong, H.S., Howell, M., Trotter, E., Papaxoinis, G., Miller, C., Nonaka, D., Brognard, J., Mansoor, W.

Journal:

Year:

2017

Language:

english

File:

PDF, 74 KB

english, 2017

30

Survival of head and neck cancer cells relies upon LZK kinase-mediated stabilization of mutant p53

Edwards, Zoe C, Trotter, Eleanor W, Torres-Ayuso, Pedro, Chapman, Phil, Wood, Henry M, Nyswaner, Katherine, Brognard, John

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 6.13 MB

english, 2017

31

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

Testoni, E., Stephenson, N. L., Torres-Ayuso, P., Marusiak, A. A., Trotter, E. W., Hudson, A., Hodgkinson, C. L., Morrow, C. J., Dive, C., Brognard, J.

Journal:

EMBO Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

32

Protein kinase Cα gain-of-function variant in Alzheimer’s disease displays enhanced catalysis by a mechanism that evades down-regulation

Callender, Julia A., Yang, Yimin, Lordén, Gema, Stephenson, Natalie L., Jones, Alexander C., Brognard, John, Newton, Alexandra C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

33

Shipping Out MEK Inhibitor Resistance with SHP2 Inhibitors

Torres-Ayuso, Pedro, Brognard, John

Journal:

Cancer Discovery

Year:

2018

Language:

english

File:

PDF, 6.80 MB

english, 2018

34

Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets

Torres-Ayuso, Pedro, Brognard, John

Journal:

Year:

2019

File:

PDF, 1.07 MB

2019

35

The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells

Hoang, Van T, Nyswaner, Katherine, Torres-Ayuso, Pedro, Brognard, John

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 17.75 MB

2020